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DHFR (NM_000791) Human Mass Spec Standard

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SKU
PH300089
DHFR MS Standard C13 and N15-labeled recombinant protein (NP_000782)
Size:
10 ug
  $3,360.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA500517 Anti-DHFR (Dihydrofolate reductase) mouse monoclonal antibody, clone OTI3A11 (formerly 3A11) 100 ul
$447.00
LY400271 Transient overexpression lysate of dihydrofolate reductase (DHFR) (as WB positive control) 100 ug
$436.00

Other products for "DHFR or NM_000791"

Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200089
Predicted MW 21.5 kDa
Protein Sequence
Protein Sequence
>RC200089 protein sequence
Red=Cloning site Green=Tags(s)

MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKG
RINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIM
QDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_000782
RefSeq Size 3932
RefSeq ORF 561
Synonyms DHFRP1; DYR
Locus ID 1719
UniProt ID P00374
Cytogenetics 5q14.1
Summary Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Mar 2014
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Folate biosynthesis, Metabolic pathways, One carbon pool by folate
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Other "DHFR" proteins (3)
SKU Description Size Price
LC400271 Lyophilized DHFR HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400271 Transient overexpression lysate of dihydrofolate reductase (DHFR) (as WB positive control) 100 ug
$436.00
TP300089 Recombinant protein of human dihydrofolate reductase (DHFR), 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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