Atg7 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN301741BN

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Atg7 - mouse gene knockout kit via CRISPR, HDR mediated

HDR-mediated knockout kit validation

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USD 1,290.00

4 Weeks

    • 1 kit

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Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Donor DNA mBFP-Neo
Symbol Atg7
Locus ID 74244
Kit Components

KN301741G1, Atg7 gRNA vector 1 in pCas-Guide CRISPR vector

KN301741G2, Atg7 gRNA vector 2 in pCas-Guide CRISPR vector

KN301741BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001253717, NM_001253718, NM_028835
Synonyms 1810013K23Rik; Agp7; Apg7l; Atg7l; Gm21553
Summary This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]


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Customer Reviews 
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
68 Mouse Clones
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