beta Actin (beta-Actin) Mouse Monoclonal Antibody [Clone ID: OTI1]

Name: beta Actin (beta-Actin) Mouse Monoclonal Antibody [Clone ID: OTI1]
SKU: TA811000

CAT#: TA811000

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beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control

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Citations (36)

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USD 295.00

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Product Data
Clone Name	OTI1
Applications	WB
Recommended Dilution	WB 1:2000
Reactivity	Human, Monkey, Mouse, Rat, Dog
Host	Mouse
Isotype	IgG3
Clonality	Monoclonal
Immunogen	Synthetic peptide corresponding to the N terminal of human beta-actin conjugated to KLH.
Formulation	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Storage	Store at -20°C as received.
Stability	Stable for 12 months from date of receipt.
Predicted Protein Size	41.6 kDa
Gene Name	actin, beta
Database Link	NP_001092 Entrez Gene 11461 Mouse Entrez Gene 81822 Rat Entrez Gene 403580 Dog Entrez Gene 574285 Monkey Entrez Gene 60 Human
Synonyms	BRWS1; PS1TP5BP1
Reference Data
Protein Families	ES Cell Differentiation/IPS
Protein Pathways	Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, Tight junction, Vibrio cholerae infection, Viral myocarditis

Citations (36)

The use of this Antibodies has been cited in the following citations:
A natural flavonoid, apigenin isolated from Clerodendrum viscosum leaves, induces G2/M phase cell cycle arrest and apoptosis in MCF-7 cells through the regulation of p53 and caspase-cascade pathway ,Shendge, AK;Chaudhuri, D;Basu, T;Mandal, N;, Clin Transl Oncol 2020 ,PubMed ID 32715386 [ACTB]
Resveratrol Regulates the Expression of Genes Involved in CoQ Synthesis in Liver in Mice Fed with High Fat Diet ,Meza-Torres, C;Hernández-Camacho, JD;Cortés-Rodríguez, AB;Fang, L;Bui Thanh, T;Rodríguez-Bies, E;Navas, P;López-Lluch, G;, Antioxidants (Basel) 2020 ,PubMed ID 32429295 [BETA-ACTIN]
Chemotherapy-induced pyroptosis is mediated by BAK/BAX-caspase-3-GSDME pathway and inhibited by 2-bromopalmitate ,Hu, L;Chen, M;Chen, X;Zhao, C;Fang, Z;Wang, H;Dai, H;, Cell Death Dis 2020 ,PubMed ID 32332857 [BETA-ACTIN]
Proteostasis regulators as potential rescuers of PMM2 activity ,Vilas, A;Yuste-Checa, P;Gallego, D;Desviat, LR;Ugarte, M;Pérez-Cerda, C;Gámez, A;Pérez, B;, Biochim Biophys Acta Mol Basis Dis 2020 ,PubMed ID 32222543 [BETA-ACTIN]
High glucose concentration produces a short-term increase in pERK1/2 and p85 proteins, having a direct angiogenetic effect by an action similar to VEGF ,Sasso, FC;Zuchegna, C;Tecce, MF;Capasso, A;Adinolfi, LE;Romano, A;Bartollino, S;Porcellini, A;Costagliola, C;, Acta Diabetol 2020 ,PubMed ID 32130518 [ACTB]
Uev1A promotes breast cancer cell survival and chemoresistance through the AKT-FOXO1-BIM pathway ,Wu, Z;Niu, T;Xiao, W;, Cancer Cell Int. 2019 ,PubMed ID 31827405 [BETA-ACTIN]
Protective functions of Lycium barbarum polysaccharides in H2O2-injured vascular endothelial cells through anti-oxidation and anti-apoptosis effects ,Xue, S;Hu, X;Zhu, L;Nie, L;Li, G;, Biomed Rep 2019 ,PubMed ID 31632668 [BETA-ACTIN]
The modification of ferroptosis and abnormal lipometabolism through overexpression and knockdown of potential prognostic biomarker perilipin2 in gastric carcinoma ,Sun, X;Yang, S;Feng, X;Zheng, Y;Zhou, J;Wang, H;Zhang, Y;Sun, H;He, C;, Gastric Cancer 2019 ,PubMed ID 31520166 [BETA-ACTIN]
Effect of curcumin extract against oxidative stress on both structure and deformation capability of red blood cell ,Yang, Q;Noviana, M;Zhao, Y;Chen, D;Wang, X;, J Biomech 2019 ,PubMed ID 31443943 [ACTB]
S-allyl-l-cysteine (SAC) protects hepatocytes from alcohol-induced apoptosis ,Chen, P;Hu, M;Liu, F;Yu, H;Chen, C;, FEBS Open Bio 2019 ,PubMed ID 31161729 [ACTB]
EAE-induced upregulation of mitochondrial MnSOD is associated with increases of mitochondrial SGK1 and Tom20 protein in the mouse kidney cortex ,Hira, S;Packialakshmi, B;Zhou, X;, J Physiol Sci 2019 ,PubMed ID 31177508 [ACTB]
Dual actions of norathyriol as a new candidate hypouricaemic agent: uricosuric effects and xanthine oxidase inhibition ,Lin, H;Tu, C;Niu, Y;Li, F;Yuan, L;Li, N;Xu, A;Gao, L;Li, L;, Eur. J. Pharmacol. 2019 ,PubMed ID 31009635 [ACTB]
Salidroside inhibits migration and invasion of poorly differentiated thyroid cancer cells ,Shang, H;Wang, S;Yao, J;Guo, C;Dong, J;Liao, L;, Thorac Cancer 2019 ,PubMed ID 31120636 [ACTB]
Aberrant PD-1 ligand expression contributes to the myocardial inflammatory injury caused by Coxsackievirus B infection ,Wang, T;Chen, S;Wang, X;Huang, Y;Qiu, J;Fei, Y;Chaulagain, A;Chen, Y;Wang, Y;Lin, L;Yan, B;Wang, Y;Wang, W;Zhao, W;Zhong, Z;, Antiviral Res. 2019 ,PubMed ID 30904424 [BETA-ACTIN]
Overexpression of grainyhead-like transcription factor 2 is associated with poor prognosis in human pancreatic carcinoma ,Wang, G;Pan, J;Zhang, L;Wang, C;, Oncol Lett 2019 ,PubMed ID 30675204 [BETA-ACTIN]
Moringa oleifera Leaf Petroleum Ether Extract Inhibits Lipogenesis by Activating the AMPK Signaling Pathway ,Xie, J;Wang, Y;Jiang, W;Luo, X;Dai, T;Peng, L;Song, S;Li, L;Tao, L;Shi, C;Hao, R;Xiao, R;Tian, Y;Sheng, J;, Front. Pharmacol. 2018 ,PubMed ID 30618744 [ACTB]
Overexpression of grainyhead‑like transcription factor 2 is associated with poor prognosis in human pancreatic carcinoma ,Wang, G;Pan, J;Zhang, L;Wang, C;, Oncol Lett 2018 [BETA-ACTIN]
Pirfenidone suppresses bleomycin-induced pulmonary fibrosis and periostin expression in rats ,Song, X;Yu, W;Guo, F;, Exp Ther Med 2018 ,PubMed ID 30186404 [BETA-ACTIN]
Emodin Attenuates Autophagy Response to Protect the Pancreas From Acute Pancreatitis Failure ,Yu, X;Li, C;Song, H;Wang, X;Guo, Y;Cui, L;Liu, X;Chi, C;Liu, R;Yin, C;, Pancreas 2018 ,PubMed ID 29912852 [ACTB]
Role of microRNA-21 in uveal melanoma cell invasion and metastasis by regulating p53 and its downstream protein ,Wang, YC;Yang, X;Wei, WB;Xu, XL;, Int J Ophthalmol 2018 ,PubMed ID 30140627 [ACTB]
An ellagic acid isolated from Clerodendrum viscosum leaves ameliorates iron-overload induced hepatotoxicity in Swiss albino mice through inhibition of oxidative stress and the apoptotic pathway ,Shendge, AK;Basu, T;Panja, S;Chaudhuri, D;Mandal, N;, Biomed. Pharmacother. 2018 ,PubMed ID 29990833 [ACTB]
High C-X-C motif chemokine 5 expression is associated with malignant phenotypes of prostate cancer cells via autocrine and paracrine pathways ,Qi, Y;Zhao, W;Li, M;Shao, M;Wang, J;Sui, H;Yu, H;Shao, W;Gui, S;Li, J;Jia, X;Jiang, D;Li, Y;Zhang, P;Wang, S;Wang, W;, Int. J. Oncol. 2018 ,PubMed ID 29749439 [BETA-ACTIN]
MicroRNA-644a promotes apoptosis of hepatocellular carcinoma cells by downregulating the expression of heat shock factor 1 ,Liang, W;Liao, Y;Li, Z;Wang, Y;Zheng, S;Xu, X;Ran, F;Tang, B;Wang, Z;, Cell Commun. Signal 2018 ,PubMed ID 29898735 [ACTB]
SKLB-23bb, A HDAC6-Selective Inhibitor, Exhibits Superior and Broad-Spectrum Antitumor Activity via Additionally Targeting Microtubules ,Wang, F;Zheng, L;Yi, Y;Yang, Z;Qiu, Q;Wang, X;Yan, W;Bai, P;Yang, J;Li, D;Pei, H;Niu, T;Ye, H;Nie, C;Hu, Y;Yang, S;Wei, Y;Chen, L;, Mol. Cancer Ther. 2018 ,PubMed ID 29610282 [ACTB]
A natural antioxidant, tannic acid mitigates iron-overload induced hepatotoxicity in Swiss albino mice through ROS regulation ,Basu, T;Panja, S;Shendge, AK;Das, A;Mandal, N;, Environ. Toxicol. 2018 ,PubMed ID 29446234 [ACTB]
Pre-B cell leukemia transcription factor 3 induces inflammatory responses in human umbilical vein endothelial cells and murine sepsis via acting a competing endogenous RNA for high mobility group box 1 protein ,Zhang, Y;Feng, J;Cui, J;Yang, G;Zhu, X;, Mol Med Rep 2018 ,PubMed ID 29484406 [ACTB]
Inhibition of FASN expression enhances radiosensitivity in human non-small cell lung cancer ,Zhan, N;Li, B;Xu, X;Xu, J;Hu, S;, Oncol Lett 2018 [BETA-ACTIN]
Growth differentiation factor‑5 induces tenomodulin expression via phosphorylation of p38 and promotes viability of murine mesenchymal stem cells from compact bone ,Qu, Y;Zhou, L;Lv, B;Wang, C;Li, P;, Mol Med Rep 2017 ,PubMed ID 29286087 [beta Actin]
T-cell immunoglobulin mucin-3 as a potential inducer of the epithelial-mesenchymal transition in hepatocellular carcinoma ,Lin, H;Yang, B;Teng, M;, Oncol Lett 2017 ,PubMed ID 29113224 [ACTB]
FMNL2 destabilises COMMD10 to activate NF-κB pathway in invasion and metastasis of colorectal cancer ,Yang, SS;Li, XM;Yang, M;Ren, XL;Hu, JL;Zhu, XH;Wang, FF;Zeng, ZC;Li, JY;Cheng, ZQ;Liao, WT;Ding, YQ;Guan, J;Liang, L;, Br. J. Cancer 2017 ,PubMed ID 28817833 [BETA]
CCDC134 serves a crucial role in embryonic development ,Yu, B;Zhang, T;Xia, P;Gong, X;Qiu, X;Huang, J;, Int. J. Mol. Med.2017 ,PubMed ID 29115376 [ACTB]
Inhibition of autophagy potentiates the proliferation inhibition activity of microRNA‑7 in human hepatocellular carcinoma cells ,Wang, Y;Wang, Q;Song, J;, Oncology Letters 2017 [BETA-ACTIN]
Heat shock factor 1 inhibits the mitochondrial apoptosis pathway by regulating second mitochondria-derived activator of caspase to promote pancreatic tumorigenesis ,Liang, W;Liao, Y;Zhang, J;Huang, Q;Luo, W;Yu, J;Gong, J;Zhou, Y;Li, X;Tang, B;He, S;Yang, J;, J. Exp. Clin. Cancer Res. 2017 ,PubMed ID 28482903 [ACTB]
Protocadherin 7 inhibits cell migration and invasion through E-cadherin in gastric cancer ,Chen, HF;Ma, RR;He, JY;Zhang, H;Liu, XL;Guo, XY;Gao, P;, Tumour Biol. 2017 ,PubMed ID 28381163 [ACTB]
MicroRNA-181c Ameliorates Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats ,Fang, C;Li, Q;Min, G;Liu, M;Cui, J;Sun, J;Li, L;, Mol. Neurobiol 2016 ,PubMed ID 27933582 [ACTB]
Aging asymmetry: systematic survey of changes in age-related biomarkers in the annual fish Nothobranchius guentheri ,Dong, Y;Cui, P;Li, Z;Zhang, S;, Fish Physiol. Biochem. 2016 ,PubMed ID 27614442 [ACTB]

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Antibody Resources
Product Overview Video: UltraMAB Product Overview Video: TrueMAB Webinar Recording: UltraMAB Video Tutorial: Video Tutorial: Antibody specificity and Knockout(KO) lysates Western Blot Protocol IHC Protocol IF Protocol FACS Protocol Immunoprecipitation (IP) Protocol IP protocol with magnetic beads

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SKU	Description	Size	Price
TA811000S	beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control	30 ul	USD 159.00

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TA811000S

beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control

USD 159.00

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Clone ID reveals the Source of Monoclonal Antibodies