beta Actin (ACTB) (NM_001101) Human Recombinant Protein
Recombinant protein of human actin, beta (ACTB)
Specifications
Product Data | |
Description | Recombinant protein of human actin, beta (ACTB) |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence | Recombinant protein was produced with TrueORF clone, RC203643. Click on the TrueORF clone link to view cDNA and protein sequences. |
Tag | C-Myc/DDK |
Predicted MW | 41.6 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001092 |
Locus ID | 60 |
Refseq Size | 1793 |
Cytogenetics | 7p22.1 |
Refseq ORF | 1125 |
Synonyms | BRWS1; PS1TP5BP1 |
Summary | This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome. [provided by RefSeq, Aug 2017] |
Protein Families | ES Cell Differentiation/IPS |
Protein Pathways | Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, Tight junction, Vibrio cholerae infection, Viral myocarditis |
Citations (3)
The use of this Proteins has been cited in the following citations: |
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The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase
,Seervai, RNH;Jangid, RK;Karki, M;Tripathi, DN;Jung, SY;Kearns, SE;Verhey, KJ;Cianfrocco, MA;Millis, BA;Tyska, MJ;Mason, FM;Rathmell, WK;Park, IY;Dere, R;Walker, CL;,
Sci Adv 2020
,PubMed ID 33008892
[ACTB]
|
SETD2 is an actin lysine methyltransferase
,Seervai, RNH;Jangid, RK;Karki, M;Tripathi, DN;,
bioRxiv 2020
[ACTB]
|
Myeloid-Derived Lymphatic Endothelial Cell Progenitors Significantly Contribute to Lymphatic Metastasis in Clinical Breast Cancer
,Volk-Draper, L;Patel, R;Bhattarai, N;Yang, J;Wilber, A;DeNardo, D;Ran, S;,
Am. J. Pathol. 2019
,PubMed ID 31421071
[ACTB]
|
Documents
FAQs |
SDS |
Resources
Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC420311 | ACTB HEK293T cell transient overexpression lysate (as WB positive control) |
USD 110.00 |
|
LY420311 | Transient overexpression lysate of actin, beta (ACTB) |
USD 360.00 |
|
PH303643 | ACTB MS Standard C13 and N15-labeled recombinant protein (NP_001092) |
USD 2,260.00 |
|
TP720518 | Recombinant protein of human actin, beta (ACTB) |
USD 300.00 |
USD 350.00
USD 169.00