Mouse Bsg activation kit by CRISPRa

CAT#: GA200444

Bsg CRISPRa kit - CRISPR gene activation of mouse basigin

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Bsg
• Locus ID: 12215
• Kit Components:

  GA200444G1, Bsg gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA200444G2, Bsg gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA200444G3, Bsg gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001077184, NM_009768
• UniProt ID: P18572
• Synonyms: AI115436; AI325119; CD147; EMMPRIN; HT-7
• Summary: Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3, SLC16A8, SLC16A11 and SLC16A12 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.[UniProtKB/Swiss-Prot Function]