Human FOXO3 activation kit by CRISPRa

CAT#: GA101619

FOXO3 CRISPRa kit - CRISPR gene activation of human forkhead box O3

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: FOXO3
• Locus ID: 2309
• Kit Components:

  GA101619G1, FOXO3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101619G2, FOXO3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101619G3, FOXO3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001455, NM_201559
• UniProt ID: O43524
• Synonyms: AF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A
• Summary: This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]