F11r (NM_053796) Rat Tagged ORF Clone Lentiviral Particle

SKU RR208210L3V

Lenti ORF particles, F11r (Myc-DDK-tagged ORF) - Rat F11 receptor (F11r), 200ul, >10^7 TU/mL

Product Data

• Type: Rat Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: F11r
• Synonyms: Jam1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RR208210).
• ACCN: NM_053796
• ORF Size: 900 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_053796.1, NP_446248.1
• RefSeq Size: 1895 bp
• RefSeq ORF: 903 bp
• Locus ID: 116479
• UniProt ID: Q9JHY1
• Cytogenetics: 13q24
• Summary: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration.[UniProtKB/Swiss-Prot Function]