Fbxl15 (NM_001107603) Rat Tagged ORF Clone Lentiviral Particle

SKU RR206667L3V

Lenti ORF particles, Fbxl15 (Myc-DDK-tagged ORF) - Rat F-box and leucine-rich repeat protein 15 (Fbxl15), 200ul, >10^7 TU/mL

Product Data

• Type: Rat Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Fbxl15
• Synonyms: RGD1306444
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RR206667).
• ACCN: NM_001107603
• ORF Size: 900 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001107603.1, NP_001101073.1
• RefSeq Size: 1346 bp
• RefSeq ORF: 903 bp
• Locus ID: 309453
• UniProt ID: D4ABB4
• Cytogenetics: 1q54
• Summary: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation. Also mediates ubiquitination of SMURF2 and WWP2 (By similarity). Required for bone mass maintenance.[UniProtKB/Swiss-Prot Function]