FGD5 (NM_152536) Human Tagged ORF Clone Lentiviral Particle
SKU
RC229441L1V
Lenti ORF particles, FGD5 (Myc-DDK-tagged)-Human FYVE, RhoGEF and PH domain containing 5 (FGD5), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | FGD5 |
Synonyms | ZFYVE23 |
Vector | pLenti-C-Myc-DDK |
Mammalian Cell Selection | None |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC229441).
|
ACCN | NM_152536 |
ORF Size | 4386 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_152536.3 |
RefSeq ORF | 4389 bp |
Locus ID | 152273 |
UniProt ID | Q6ZNL6 |
Cytogenetics | 3p25.1 |
Domains | FYVE, PH, RhoGEF |
MW | 159.7 kDa |
Summary | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.[UniProtKB/Swiss-Prot Function] |
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