Apolipoprotein L 1 (APOL1) (NM_001136540) Human Tagged ORF Clone Lentiviral Particle

SKU RC226566L3V

Lenti ORF particles, APOL1 (Myc-DDK tagged) - Human apolipoprotein L, 1 (APOL1), transcript variant 3, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Apolipoprotein L 1
• Synonyms: APO-L; APOL; APOL-I; FSGS4
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC226566).
• ACCN: NM_001136540
• ORF Size: 1194 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001136540.1, NP_001130012.1
• RefSeq Size: 2924 bp
• RefSeq ORF: 1197 bp
• Locus ID: 8542
• UniProt ID: O14791
• Cytogenetics: 22q12.3
• Protein Families: Secreted Protein, Transmembrane
• MW: 43.9 kDa
• Summary: This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]