Alpha Fodrin (SPTAN1) (NM_001130438) Human Tagged ORF Clone Lentiviral Particle

SKU RC226485L1V

Lenti ORF particles, SPTAN1 (Myc-DDK tagged) - Human spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) (SPTAN1), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Alpha Fodrin
• Synonyms: DEE5; EIEE5; NEAS; SPTA2
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC226485).
• ACCN: NM_001130438
• ORF Size: 7431 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001130438.2, NP_001123910.1
• RefSeq Size: 7907 bp
• RefSeq ORF: 7434 bp
• Locus ID: 6709
• UniProt ID: Q13813
• Cytogenetics: 9q34.11
• Protein Families: Druggable Genome
• Protein Pathways: Tight junction
• MW: 285.5 kDa
• Summary: Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]