TMPRSS3 (NM_032401) Human Tagged ORF Clone Lentiviral Particle

SKU RC224957L3V

Lenti ORF particles, TMPRSS3 (Myc-DDK tagged) - Human transmembrane protease, serine 3 (TMPRSS3), transcript variant B, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: TMPRSS3
• Synonyms: DFNB8; DFNB8, DFNB10, ECHOS1, TADG12; DFNB10; ECHOS1; OTTHUMP00000109345; serine protease TADG12; TADG12; transmembrane protease, serine 3
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224957).
• ACCN: NM_032401
• ORF Size: 981 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_032401.1, NP_115777.1
• RefSeq Size: 2554 bp
• RefSeq ORF: 983 bp
• Locus ID: 64699
• Cytogenetics: 21q22.3
• Domains: Tryp_SPc
• Protein Families: Druggable Genome, Protease, Transmembrane
• MW: 36.2 kDa
• Summary: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]