Ceruloplasmin (CP) (NM_000096) Human Tagged ORF Clone Lentiviral Particle

SKU RC224598L3V

Lenti ORF particles, CP (Myc-DDK tagged) - Human ceruloplasmin (ferroxidase) (CP), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Ceruloplasmin
• Synonyms: CP-2
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224598).
• ACCN: NM_000096
• ORF Size: 3195 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_000096.1, NP_000087.1
• RefSeq Size: 3321 bp
• RefSeq ORF: 3198 bp
• Locus ID: 1356
• UniProt ID: P00450
• Cytogenetics: 3q24-q25.1
• Domains: Cu-oxidase
• Protein Families: Druggable Genome
• Protein Pathways: Porphyrin and chlorophyll metabolism
• MW: 122.21 kDa
• Summary: The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012]