FLASH (CASP8AP2) (NM_012115) Human Tagged ORF Clone Lentiviral Particle

SKU RC224342L1V

Lenti ORF particles, CASP8AP2 (Myc-DDK tagged) - Human caspase 8 associated protein 2 (CASP8AP2), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: FLASH
• Synonyms: CED-4; FLASH; RIP25
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224342).
• ACCN: NM_012115
• ORF Size: 5946 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_012115.2
• RefSeq Size: 6782 bp
• RefSeq ORF: 5949 bp
• Locus ID: 9994
• UniProt ID: Q9UKL3
• Cytogenetics: 6q15
• Protein Families: Druggable Genome
• MW: 222.7 kDa
• Summary: This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008]