SRGAP2 (NM_015326) Human Tagged ORF Clone Lentiviral Particle

SKU RC224139L3V

Lenti ORF particles, SRGAP2 (Myc-DDK tagged) - Human SLIT-ROBO Rho GTPase activating protein 2 (SRGAP2), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: SRGAP2
• Synonyms: ARHGAP34; FNBP2; SRGAP2A; SRGAP3
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224139).
• ACCN: NM_015326
• ORF Size: 3213 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_015326.1
• RefSeq Size: 6305 bp
• RefSeq ORF: 3216 bp
• Locus ID: 23380
• UniProt ID: O75044
• Cytogenetics: 1q32.1
• Protein Pathways: Axon guidance
• MW: 120.7 kDa
• Summary: This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014]