Gasdermin like (GSDMB) (NM_018530) Human Tagged ORF Clone Lentiviral Particle

SKU RC224054L3V

Lenti ORF particles, GSDMB (Myc-DDK-tagged)-Human gasdermin B (GSDMB), transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Gasdermin like
• Synonyms: GSDMB-1; GSDML; PP4052; PRO2521
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224054).
• ACCN: NM_018530
• ORF Size: 1182 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_018530.2, NP_061000.2
• RefSeq Size: 1646 bp
• RefSeq ORF: 1185 bp
• Locus ID: 55876
• UniProt ID: Q8TAX9
• Cytogenetics: 17q21.1
• Domains: DFNA5
• MW: 45 kDa
• Summary: This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq, Nov 2016]