JMJD1C (NM_004241) Human Tagged ORF Clone Lentiviral Particle

SKU RC223872L1V

Lenti ORF particles, JMJD1C (Myc-DDK tagged) - Human jumonji domain containing 1C (JMJD1C), transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: JMJD1C
• Synonyms: KDM3C; TRIP-8; TRIP8
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC223872).
• ACCN: NM_004241
• ORF Size: 6909 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_004241.2, NP_004232.2
• RefSeq Size: 8415 bp
• RefSeq ORF: 6911 bp
• Locus ID: 221037
• Cytogenetics: 10q21.3
• Protein Families: Druggable Genome
• MW: 256.6 kDa
• Summary: The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]