RNF14 (NM_183400) Human Tagged ORF Clone Lentiviral Particle

SKU
RC223362L1V
Lenti ORF particles, RNF14 (Myc-DDK tagged) - Human ring finger protein 14 (RNF14), transcript variant 4, 200ul, >10^7 TU/mL
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    Expression-ready ORF plasmid in lenti backbone

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$1,007.00
3 Weeks*
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Target Symbol RNF14
Synonyms ARA54; HFB30; HRIHFB2038; TRIAD2
Vector pLenti-C-Myc-DDK
Mammalian Cell Selection None
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC223362).
ACCN NM_183400
ORF Size 1422 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_183400.1
RefSeq Size 2970 bp
RefSeq ORF 1425 bp
Locus ID 9604
UniProt ID Q9UBS8
Cytogenetics 5q31.3
Protein Families Druggable Genome, Transcription Factors
MW 53.7 kDa
Summary The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011]
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