DCTD (NM_001012732) Human Tagged ORF Clone Lentiviral Particle
SKU
RC223090L3V
Lenti ORF particles, DCTD (Myc-DDK tagged) - Human dCMP deaminase (DCTD), transcript variant 1, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | DCTD |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC223090).
|
ACCN | NM_001012732 |
ORF Size | 567 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_001012732.1, NP_001012750.1 |
RefSeq Size | 2042 bp |
RefSeq ORF | 570 bp |
Locus ID | 1635 |
UniProt ID | P32321 |
Cytogenetics | 4q35.1 |
Protein Pathways | Metabolic pathways, Pyrimidine metabolism |
MW | 20.8 kDa |
Summary | The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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