OVCA1 (DPH1) (NM_001383) Human Tagged ORF Clone Lentiviral Particle

SKU RC221955L1V

Lenti ORF particles, DPH1 (Myc-DDK tagged) - Human DPH1 homolog (S. cerevisiae) (DPH1), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: OVCA1
• Synonyms: DEDSSH; DPH2L; DPH2L1; OVCA1
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC221955).
• ACCN: NM_001383
• ORF Size: 1329 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001383.3
• RefSeq Size: 2200 bp
• RefSeq ORF: 1317 bp
• Locus ID: 1801
• UniProt ID: Q9BZG8
• Cytogenetics: 17p13.3
• Domains: Diphthamide_syn
• MW: 48.6 kDa
• Summary: The protein encoded by this gene is an enzyme involved in the biosynthesis of diphthamide, a modified histidine found only in elongation factor-2 (EEF2). Diphthamide residues in EEF2 are targeted for ADP-ribosylation by diphtheria toxin and Pseudomonas exotoxin A. Defects in this gene have been associated with both ovarian cancer and autosomal recessive intellectual disability with short stature, craniofacial, and ectodermal anomalies. [provided by RefSeq, Oct 2016]