alpha Lactalbumin (LALBA) (NM_002289) Human Tagged ORF Clone Lentiviral Particle
SKU
RC221214L1V
Lenti ORF particles, LALBA (Myc-DDK tagged) - Human lactalbumin, alpha- (LALBA), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | alpha Lactalbumin |
Synonyms | LYZG |
Vector | pLenti-C-Myc-DDK |
Mammalian Cell Selection | None |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC221214).
|
ACCN | NM_002289 |
ORF Size | 426 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_002289.2 |
RefSeq Size | 742 bp |
RefSeq ORF | 429 bp |
Locus ID | 3906 |
UniProt ID | P00709 |
Cytogenetics | 12q13.11 |
Protein Families | Secreted Protein |
Protein Pathways | Galactose metabolism |
MW | 16.22 kDa |
Summary | This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells. [provided by RefSeq, Jul 2008] |
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