INPP5F (OCRL) (NM_000276) Human Tagged ORF Clone Lentiviral Particle

SKU RC220672L1V

Lenti ORF particles, OCRL (Myc-DDK tagged) - Human oculocerebrorenal syndrome of Lowe (OCRL), transcript variant a, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: INPP5F
• Synonyms: Dent-2; DENT2; INPP5F; LOCR; NPHL2; OCRL-1; OCRL1
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC220672).
• ACCN: NM_000276
• ORF Size: 2703 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_000276.3
• RefSeq Size: 5165 bp
• RefSeq ORF: 2706 bp
• Locus ID: 4952
• UniProt ID: Q01968
• Cytogenetics: Xq26.1
• Domains: Exo_endo_phos, IPPc, RhoGAP
• Protein Families: Druggable Genome
• Protein Pathways: Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system
• MW: 104 kDa
• Summary: This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]