LRRK1 (NM_024652) Human Tagged ORF Clone Lentiviral Particle

SKU RC218814L1V

Lenti ORF particles, LRRK1 (Myc-DDK tagged) - Human leucine-rich repeat kinase 1 (LRRK1), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: LRRK1
• Synonyms: RIPK6; Roco1
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC218814).
• ACCN: NM_024652
• ORF Size: 6045 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_024652.3, NP_078928.3
• RefSeq Size: 7647 bp
• RefSeq ORF: 6048 bp
• Locus ID: 79705
• UniProt ID: Q38SD2
• Cytogenetics: 15q26.3
• Protein Families: Druggable Genome, Protein Kinase
• MW: 225.2 kDa
• Summary: This gene encodes a multi-domain protein that is a leucine-rich repeat kinase and a GDP/GTP binding protein. The encoded protein is thought to play a role in the regulation of bone mass. Mice lacking a similar gene showed severe osteopetrosis, increased bone mineralization and decreased bone resorption. [provided by RefSeq, Jan 2017]