PKHD1 (NM_138694) Human Tagged ORF Clone Lentiviral Particle

SKU RC218550L1V

Lenti ORF particles, PKHD1 (Myc-DDK tagged) - Human polycystic kidney and hepatic disease 1 (autosomal recessive) (PKHD1), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: PKHD1
• Synonyms: ARPKD; FCYT; FPC; PKD4; TIGM1
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC218550).
• ACCN: NM_138694
• ORF Size: 12222 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_138694.2, NP_619639.2
• RefSeq Size: 16235 bp
• RefSeq ORF: 12225 bp
• Locus ID: 5314
• UniProt ID: P08F94
• Cytogenetics: 6p12.3-p12.2
• Protein Families: Druggable Genome, Transmembrane
• MW: 446.5 kDa
• Summary: The protein encoded by this gene is predicted to have a single transmembrane (TM)-spanning domain and multiple copies of an immunoglobulin-like plexin-transcription-factor domain. Alternative splicing results in two transcript variants encoding different isoforms. Other alternatively spliced transcripts have been described, but the full length sequences have not been determined. Several of these transcripts are predicted to encode truncated products which lack the TM and may be secreted. Mutations in this gene cause autosomal recessive polycystic kidney disease, also known as polycystic kidney and hepatic disease-1. [provided by RefSeq, Jul 2008]