NIPP1 (PPP1R8) (NM_002713) Human Tagged ORF Clone Lentiviral Particle

SKU
RC216856L3V
Lenti ORF particles, PPP1R8 (Myc-DDK-tagged)-Human protein phosphatase 1, regulatory (inhibitor) subunit 8 (PPP1R8), transcript variant 3, 200ul, >10^7 TU/mL
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    Expression-ready ORF plasmid in lenti backbone

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$715.00
10 Weeks*
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Target Symbol NIPP1
Synonyms ARD-1; ARD1; NIPP-1; NIPP1; PRO2047
Vector pLenti-C-Myc-DDK-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC216856).
ACCN NM_002713
ORF Size 381 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_002713.3
RefSeq Size 2558 bp
RefSeq ORF 384 bp
Locus ID 5511
UniProt ID Q12972
Cytogenetics 1p35.3
Protein Families Druggable Genome, Transcription Factors
MW 13.3 kDa
Summary This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008]
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