Sulfatase 1 (SULF1) (NM_015170) Human Tagged ORF Clone Lentiviral Particle
SKU
RC216632L2V
Lenti ORF particles, SULF1 (mGFP-tagged) - Human sulfatase 1 (SULF1), transcript variant 3, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | Sulfatase 1 |
Synonyms | SULF-1 |
Vector | pLenti-C-mGFP |
Mammalian Cell Selection | None |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC216632).
|
ACCN | NM_015170 |
ORF Size | 2613 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_015170.1 |
RefSeq Size | 5699 bp |
RefSeq ORF | 2616 bp |
Locus ID | 23213 |
UniProt ID | Q8IWU6 |
Cytogenetics | 8q13.2-q13.3 |
Protein Families | Druggable Genome |
MW | 100.8 kDa |
Summary | This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
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