Sulfatase 1 (SULF1) Rabbit Polyclonal Antibody

SKU TA351768

Rabbit Polyclonal Anti-SULF1 Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 10-50; Positive control: Human liver cancer; Predicted cell location: Cytoplasm and Cell membrane
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human SULF1
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: sulfatase 1
• Database Link:
  NP_055985
  Q8IWU6
• Background: This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants.
• Synonyms: HSULF-1; SULF-1

Reference Data

• Protein Families: Druggable Genome