Folate Receptor 4 (IZUMO1R) (NM_001080486) Human Tagged ORF Clone Lentiviral Particle

SKU RC216623L3V

Lenti ORF particles, FOLR4 (Myc-DDK tagged) - Human folate receptor 4 (delta) homolog (mouse) (FOLR4), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Folate Receptor 4
• Synonyms: folate receptor 4 (delta) homolog; folate receptor 4 (delta) homolog (mouse); Folbp3
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC216623).
• ACCN: NM_001080486
• ORF Size: 729 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001080486.1, NP_001073955.1
• RefSeq Size: 732 bp
• RefSeq ORF: 731 bp
• Locus ID: 390243
• Cytogenetics: 11q21
• MW: 27.8 kDa
• Summary: Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.[UniProtKB/Swiss-Prot Function]