BPNT1 (NM_006085) Human Tagged ORF Clone Lentiviral Particle

SKU RC216622L3V

Lenti ORF particles, BPNT1 (Myc-DDK tagged) - Human 3'(2'), 5'-bisphosphate nucleotidase 1 (BPNT1), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: BPNT1
• Synonyms: HEL20; PIP
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC216622).
• ACCN: NM_006085
• ORF Size: 924 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_006085.4
• RefSeq Size: 2461 bp
• RefSeq ORF: 927 bp
• Locus ID: 10380
• UniProt ID: O95861
• Cytogenetics: 1q41
• Domains: inositol_P
• Protein Pathways: Sulfur metabolism
• MW: 33.2 kDa
• Summary: BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity. [provided by RefSeq, Jul 2008]