Thrombospondin 1 (THBS1) (NM_003246) Human Tagged ORF Clone Lentiviral Particle

SKU RC214802L1V

Lenti ORF particles, THBS1 (Myc-DDK tagged) - Human thrombospondin 1 (THBS1), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Thrombospondin 1
• Synonyms: THBS; THBS-1; TSP; TSP-1; TSP1
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214802).
• ACCN: NM_003246
• ORF Size: 3510 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_003246.2
• RefSeq Size: 5820 bp
• RefSeq ORF: 3513 bp
• Locus ID: 7057
• UniProt ID: P07996
• Cytogenetics: 15q14
• Domains: EGF, EGF_CA, TSPN, tsp_1, tsp_3, VWC
• Protein Families: Druggable Genome
• Protein Pathways: Bladder cancer, ECM-receptor interaction, Focal adhesion, p53 signaling pathway, TGF-beta signaling pathway
• MW: 129.38 kDa
• Summary: The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008]