Stabilin 2 (STAB2) (NM_017564) Human Tagged ORF Clone Lentiviral Particle
SKU
RC214781L1V
Lenti ORF particles, STAB2 (Myc-DDK tagged) - Human stabilin 2 (STAB2), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | Stabilin 2 |
Synonyms | FEEL2; FELE-2; FELL2; FEX2; HARE; SCARH1 |
Vector | pLenti-C-Myc-DDK |
Mammalian Cell Selection | None |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC214781).
|
ACCN | NM_017564 |
ORF Size | 7653 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_017564.9, NP_060034.9 |
RefSeq Size | 8266 bp |
RefSeq ORF | 7656 bp |
Locus ID | 55576 |
UniProt ID | Q8WWQ8 |
Cytogenetics | 12q23.3 |
Protein Families | Druggable Genome, Transmembrane |
MW | 276.99 kDa |
Summary | This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq, Jul 2008] |
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