CACNA1G (NM_018896) Human Tagged ORF Clone Lentiviral Particle
SKU
RC214754L1V
Lenti ORF particles, CACNA1G (Myc-DDK tagged) - Human calcium channel, voltage-dependent, T type, alpha 1G subunit (CACNA1G), transcript variant 1, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | CACNA1G |
Synonyms | Ca(V)T.1; Cav3.1; NBR13; SCA42; SCA42ND |
Vector | pLenti-C-Myc-DDK |
Mammalian Cell Selection | None |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC214754).
|
ACCN | NM_018896 |
ORF Size | 7131 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_018896.3 |
RefSeq Size | 7825 bp |
RefSeq ORF | 7134 bp |
Locus ID | 8913 |
UniProt ID | O43497 |
Cytogenetics | 17q21.33 |
Protein Families | Druggable Genome, Ion Channels: Calcium, Transmembrane |
Protein Pathways | Calcium signaling pathway, MAPK signaling pathway, Type II diabetes mellitus |
MW | 262.3 kDa |
Summary | Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011] |
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