EML4 (NM_019063) Human Tagged ORF Clone Lentiviral Particle

SKU RC214653L1V

Lenti ORF particles, EML4 (Myc-DDK-tagged)-Human echinoderm microtubule associated protein like 4 (EML4), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: EML4
• Synonyms: C2orf2; ELP120; EMAP-4; EMAPL4; ROPP120
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214653).
• ACCN: NM_019063
• ORF Size: 2943 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_019063.3
• RefSeq Size: 5539 bp
• RefSeq ORF: 2946 bp
• Locus ID: 27436
• UniProt ID: Q9HC35
• Cytogenetics: 2p21
• Domains: HELP, WD40
• Protein Families: Druggable Genome
• MW: 108.7 kDa
• Summary: This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015]