DFNA5 (GSDME) (NM_004403) Human Tagged ORF Clone Lentiviral Particle

SKU RC210515L3V

Lenti ORF particles, DFNA5 (Myc-DDK tagged) - Human deafness, autosomal dominant 5 (DFNA5), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: GSDME
• Synonyms: DFNA5; ICERE-1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210515).
• ACCN: NM_004403
• ORF Size: 1488 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_004403.2
• RefSeq Size: 2521 bp
• RefSeq ORF: 1491 bp
• Locus ID: 1687
• UniProt ID: O60443
• Cytogenetics: 7p15.3
• Domains: DFNA5
• Protein Families: Druggable Genome
• MW: 54.6 kDa
• Summary: Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]