OSTM1 (NM_014028) Human Tagged ORF Clone Lentiviral Particle
SKU
RC209871L3V
Lenti ORF particles, OSTM1 (Myc-DDK tagged) - Human osteopetrosis associated transmembrane protein 1 (OSTM1), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | OSTM1 |
Synonyms | GIPN; GL; HSPC019; OPTB5 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC209871).
|
ACCN | NM_014028 |
ORF Size | 1002 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_014028.3 |
RefSeq Size | 4467 bp |
RefSeq ORF | 1005 bp |
Locus ID | 28962 |
UniProt ID | Q86WC4 |
Cytogenetics | 6q21 |
Protein Families | Transmembrane |
MW | 37.3 kDa |
Summary | This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis. [provided by RefSeq, Jul 2008] |
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