RGS20 (NM_003702) Human Tagged ORF Clone Lentiviral Particle
SKU
RC209495L3V
Lenti ORF particles, RGS20 (Myc-DDK tagged) - Human regulator of G-protein signaling 20 (RGS20), transcript variant 2, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | RGS20 |
Synonyms | g(z)GAP; gz-GAP; RGSZ1; ZGAP1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC209495).
|
ACCN | NM_003702 |
ORF Size | 723 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_003702.2, NP_003693.2 |
RefSeq Size | 1716 bp |
RefSeq ORF | 726 bp |
Locus ID | 8601 |
UniProt ID | O76081 |
Cytogenetics | 8q11.23 |
Domains | RGS |
Protein Families | Druggable Genome |
MW | 27.1 kDa |
Summary | The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
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