BCL3 (NM_005178) Human Tagged ORF Clone Lentiviral Particle

SKU RC209116L2V

Lenti ORF particles, BCL3 (mGFP-tagged) - Human B-cell CLL/lymphoma 3 (BCL3), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: BCL3
• Synonyms: BCL4; D19S37
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209116).
• ACCN: NM_005178
• ORF Size: 1338 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_005178.3, NP_005169.1
• RefSeq Size: 1864 bp
• RefSeq ORF: 1365 bp
• Locus ID: 602
• UniProt ID: P20749
• Cytogenetics: 19q13.32
• Domains: ANK
• Protein Families: Druggable Genome, Transcription Factors
• MW: 47.4 kDa
• Summary: This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008]