FAM35A (NM_019054) Human Tagged ORF Clone Lentiviral Particle

SKU RC208697L3V

Lenti ORF particles, FAM35A (Myc-DDK tagged) - Human family with sequence similarity 35, member A (FAM35A), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: FAM35A
• Synonyms: bA163M19.1; FAM35A; FAM35A1; RINN2
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC208697).
• ACCN: NM_019054
• ORF Size: 2505 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_019054.1
• RefSeq Size: 3417 bp
• RefSeq ORF: 2508 bp
• Locus ID: 54537
• UniProt ID: Q86V20
• Cytogenetics: 10q23.2
• MW: 93.7 kDa
• Summary: Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs) (PubMed:29656893, PubMed:29789392). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection (PubMed:29656893, PubMed:29789392). Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres (PubMed:29656893).[UniProtKB/Swiss-Prot Function]