THBS4 (NM_003248) Human Tagged ORF Clone Lentiviral Particle

SKU RC208408L3V

Lenti ORF particles, THBS4 (Myc-DDK-tagged)-Human thrombospondin 4 (THBS4), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: THBS4
• Synonyms: TSP-4; TSP4
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC208408).
• ACCN: NM_003248
• ORF Size: 2883 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_003248.4
• RefSeq Size: 3233 bp
• RefSeq ORF: 2886 bp
• Locus ID: 7060
• UniProt ID: P35443
• Cytogenetics: 5q14.1
• Domains: EGF, EGF_CA, TSPN, tsp_3
• Protein Families: Druggable Genome
• Protein Pathways: ECM-receptor interaction, Focal adhesion, TGF-beta signaling pathway
• MW: 105.9 kDa
• Summary: The protein encoded by this gene belongs to the thrombospondin protein family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentamer and can bind to heparin and calcium. It is involved in local signaling in the developing and adult nervous system, and it contributes to spinal sensitization and neuropathic pain states. This gene is activated during the stromal response to invasive breast cancer. It may also play a role in inflammatory responses in Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]