DHX8 (NM_004941) Human Tagged ORF Clone Lentiviral Particle

SKU RC208403L4V

Lenti ORF particles, DHX8 (mGFP-tagged) - Human DEAH (Asp-Glu-Ala-His) box polypeptide 8 (DHX8), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: DHX8
• Synonyms: DDX8; Dhr2; HRH1; PRP22; PRPF22
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC208403).
• ACCN: NM_004941
• ORF Size: 3660 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_004941.1
• RefSeq Size: 4201 bp
• RefSeq ORF: 3663 bp
• Locus ID: 1659
• UniProt ID: Q14562
• Cytogenetics: 17q21.31
• Domains: DEAD, HA2, helicase_C, S1
• Protein Pathways: Spliceosome
• MW: 139.3 kDa
• Summary: This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]