beta 2 Microglobulin (B2M) (NM_004048) Human Tagged ORF Clone Lentiviral Particle

SKU RC207587L4V

Lenti ORF particles, B2M (mGFP-tagged) - Human beta-2-microglobulin (B2M), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: beta 2 Microglobulin
• Synonyms: IMD43
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC207587).
• ACCN: NM_004048
• ORF Size: 357 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_004048.2
• RefSeq Size: 987 bp
• RefSeq ORF: 360 bp
• Locus ID: 567
• UniProt ID: P61769
• Cytogenetics: 15q21.1
• Domains: ig, IGc1
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Antigen processing and presentation
• MW: 13.71 kDa
• Summary: This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]