BLK (NM_001715) Human Tagged ORF Clone Lentiviral Particle

SKU RC207123L4V

Lenti ORF particles, BLK (mGFP-tagged)-Human B lymphoid tyrosine kinase (BLK), 200ul, >10^7 TU/mL. Note: ORF is codon optimized

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: BLK
• Synonyms: MODY11
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC207123).
• ACCN: NM_001715
• ORF Size: 1515 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001715.2, NP_001706.2
• RefSeq Size: 2215 bp
• RefSeq ORF: 1518 bp
• Locus ID: 640
• UniProt ID: P51451
• Cytogenetics: 8p23.1
• Domains: pkinase, SH2, SH3, S_TKc, TyrKc
• Protein Families: Druggable Genome, Protein Kinase
• MW: 57.7 kDa
• Summary: This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010]