NEI3 (NEIL3) (NM_018248) Human Tagged ORF Clone Lentiviral Particle

SKU RC206838L1V

Lenti ORF particles, NEIL3 (Myc-DDK tagged) - Human nei endonuclease VIII-like 3 (E. coli) (NEIL3), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: NEI3
• Synonyms: FGP2; FPG2; hFPG2; hNEI3; NEI3; ZGRF3
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206838).
• ACCN: NM_018248
• ORF Size: 1815 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_018248.1
• RefSeq Size: 2402 bp
• RefSeq ORF: 1818 bp
• Locus ID: 55247
• UniProt ID: Q8TAT5
• Cytogenetics: 4q34.3
• Domains: Fapy_DNA_glyco, zf-RanBP
• Protein Families: Druggable Genome
• Protein Pathways: Base excision repair
• MW: 68 kDa
• Summary: NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008]