CD89 (FCAR) (NM_002000) Human Tagged ORF Clone Lentiviral Particle

SKU RC206601L1V

Lenti ORF particles, FCAR (Myc-DDK tagged) - Human Fc fragment of IgA, receptor for (FCAR), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: CD89
• Synonyms: CD89; CTB-61M7.2; FcalphaRI
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206601).
• ACCN: NM_002000
• ORF Size: 861 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_002000.2, NP_001991.1
• RefSeq Size: 1671 bp
• RefSeq ORF: 864 bp
• Locus ID: 2204
• UniProt ID: P24071
• Cytogenetics: 19q13.42
• Domains: ig, IG
• Protein Families: Transmembrane
• MW: 32.3 kDa
• Summary: This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]