VPS45A (VPS45) (NM_007259) Human Tagged ORF Clone Lentiviral Particle
SKU
RC206027L1V
Lenti ORF particles, VPS45 (Myc-DDK tagged) - Human vacuolar protein sorting 45 homolog (S. cerevisiae) (VPS45), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | VPS45A |
Synonyms | H1; H1VPS45; SCN5; VPS45A; VPS45B; VPS54A; VSP45; VSP45A |
Vector | pLenti-C-Myc-DDK |
Mammalian Cell Selection | None |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC206027).
|
ACCN | NM_007259 |
ORF Size | 1710 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_007259.3 |
RefSeq Size | 2824 bp |
RefSeq ORF | 1713 bp |
Locus ID | 11311 |
UniProt ID | Q9NRW7 |
Cytogenetics | 1q21.2 |
Domains | Sec1 |
Protein Pathways | Endocytosis |
MW | 65.1 kDa |
Summary | Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013] |
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