Gephyrin (GPHN) (NM_020806) Human Tagged ORF Clone Lentiviral Particle

SKU RC205986L1V

Lenti ORF particles, GPHN (Myc-DDK tagged) - Human gephyrin (GPHN), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Gephyrin
• Synonyms: GEPH; GPH; GPHRYN; HKPX1; MOCODC
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205986).
• ACCN: NM_020806
• ORF Size: 2307 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_020806.4
• RefSeq Size: 4318 bp
• RefSeq ORF: 2310 bp
• Locus ID: 10243
• UniProt ID: Q9NQX3
• Cytogenetics: 14q23.3-q24.1
• Domains: MoCF_biosynth, MoeA_C, MoeA_N
• Protein Families: Druggable Genome
• MW: 83.4 kDa
• Summary: This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq, Jul 2008]