Neurokinin B (TAC3) (NM_013251) Human Tagged ORF Clone Lentiviral Particle
SKU
RC205666L3V
Lenti ORF particles, TAC3 (Myc-DDK tagged) - Human tachykinin 3 (TAC3), transcript variant 1, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | Neurokinin B |
Synonyms | HH10; LncZBTB39; NK3; NKB; NKNB; PRO1155; ZNEUROK1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC205666).
|
ACCN | NM_013251 |
ORF Size | 363 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_013251.2 |
RefSeq Size | 841 bp |
RefSeq ORF | 366 bp |
Locus ID | 6866 |
UniProt ID | Q9UHF0 |
Cytogenetics | 12q13.3 |
Domains | Neurokinin_B |
Protein Families | Druggable Genome, Secreted Protein |
MW | 13.4 kDa |
Summary | This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded preproprotein is proteolytically processed to generate the mature peptide, which is primarily expressed in the central and peripheral nervous systems and functions as a neurotransmitter. This peptide is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016] |
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