GPSM2 (NM_013296) Human Tagged ORF Clone Lentiviral Particle
SKU
RC205650L3V
Lenti ORF particles, GPSM2 (Myc-DDK tagged) - Human G-protein signaling modulator 2 (GPSM2), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | GPSM2 |
Synonyms | CMCS; DFNB82; LGN; PINS |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC205650).
|
ACCN | NM_013296 |
ORF Size | 2031 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_013296.4, NP_037428.2 |
RefSeq Size | 3039 bp |
RefSeq ORF | 2055 bp |
Locus ID | 29899 |
UniProt ID | P81274 |
Cytogenetics | 1p13.3 |
Domains | GoLoco, TPR |
Protein Families | Druggable Genome |
MW | 75.8 kDa |
Summary | The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
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