SERPINB4 (NM_002974) Human Tagged ORF Clone Lentiviral Particle
SKU
RC205612L1V
Lenti ORF particles, SERPINB4 (Myc-DDK tagged) - Human serpin peptidase inhibitor, clade B (ovalbumin), member 4 (SERPINB4), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | SERPINB4 |
Synonyms | LEUPIN; PI11; SCCA-2; SCCA1; SCCA2 |
Vector | pLenti-C-Myc-DDK |
Mammalian Cell Selection | None |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC205612).
|
ACCN | NM_002974 |
ORF Size | 1170 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_002974.2 |
RefSeq Size | 1787 bp |
RefSeq ORF | 1173 bp |
Locus ID | 6318 |
UniProt ID | P48594 |
Cytogenetics | 18q21.33 |
Protein Families | Druggable Genome, Secreted Protein |
MW | 44.9 kDa |
Summary | The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation. [provided by RefSeq, Jan 2017] |
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