LGI1 (NM_005097) Human Tagged ORF Clone Lentiviral Particle

SKU RC205340L1V

Lenti ORF particles, LGI1 (Myc-DDK tagged) - Human leucine-rich, glioma inactivated 1 (LGI1), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: LGI1
• Synonyms: ADLTE; ADPAEF; ADPEAF; EPITEMPIN; EPT; ETL1; IB1099
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205340).
• ACCN: NM_005097
• ORF Size: 1671 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_005097.1
• RefSeq Size: 2366 bp
• RefSeq ORF: 1674 bp
• Locus ID: 9211
• UniProt ID: O95970
• Cytogenetics: 10q23.33
• Domains: EPTP, LRR, LRRCT, LRR_TYP
• Protein Families: Druggable Genome, Secreted Protein
• MW: 63.8 kDa
• Summary: This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]